Mythic items provide some of the strongest stats and effects players can want in Diablo 4. They are incredibly powerful, and a single one of them can easily turn your build from mediocre to excellent under the right conditions. The catch here is that Mythic Uniques are extremely rare, and unless players get very lucky during their first forays into Torment difficulty, they likely won’t get to see a Mythic Unique until much later.
In this guide, we’ll be going over each of the Mythic Unique items in Diablo 4 to help you figure out which ones will work for your build, as well as some things you might want to know about getting some for yourself.
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Diablo 4 Mythic Items List
All Mythic Uniques in Diablo 4
Item
Category
Effect
Andariel’s Visage
Helmet
Lucky Hit: Up to a 20% chance to trigger a poison nova.
Ahavarion, Spear of Lycander
Polearm
Gain a random Shrine effect for 20s after killing an Elite. Can only occur once every 30s.
Doombringer
Sword
Lucky Hit: Up to a 25% chance to deal Shadow damage to surrounding enemies and reduce their damage output for 5s.
Harlequin Crest
Helmet
Gain 20% Damage Reduction and +4 Ranks to all skills.
Heir of Perdition
Helmet
Earn Mother’s Favor, increasing your damage dealt by 60%. Briefly steal Mother’s Favor from nearby allies while slaughtering enemies.
Melted Heart of Selig
Amulet
Gain 60 Maximum Resource. When taking damage, 75% of it is drained as 2 Resource for every 1% Maximum Life you would have lost.
Nesekem, The Herald
Glaive
Randomly mark an enemy every 2s. Marked enemies are Vulnerable, and your attacks are guaranteed to be Critical and Overpowered against them. Hitting marked enemies 10 times clears the effect.
Ring of Starless Skies
Ring
Spending Resource increases your damage and reduces Resource costs.
The Grandfather
2H Sword
Increases your Critical Strike Damage by [x]100%. Stats on this item roll higher than usual.
Tyrael’s Might
Chest Armor
When your Life is full, your skills launch a Divine Barrage.
Shattered Vow
Polearm
Enemies afflicted by more Damage Over Time than remaining Life are Executed.
Shroud of False Death
Chest Armor
If you haven’t dealt damage in the last 2s, gain Stealth and 40% increased movement speed.
The majority of Mythic Uniques can be equipped by any class in Diablo 4. However, weapons like The Grandfather and Nesekem can still only be equipped by classes that can use such weapon types.
How to Get Mythic Uniques in Diablo 4
The best places to farm Mythic Uniques are boss lairs. Enemies like Andariel, Duriel, and the Harbinger of Hatred all drop Unique items once you open their treasure hoards, and each Unique that drops has a tiny chance (roughly ~1.75%) to be a Mythic Unique. Other Mythic Unique sources include:
Purveyors of Curiosity
Nightmare Dungeons
Tree of Whispers Reward Caches
Blacksmith/Jeweler Crafting
How to Craft Mythic Uniques
You craft Mythic items from the Blacksmith and Jeweler in any town, but you need to get other Mythic Uniques first. When you dismantle a Mythic item, you’ll get a Resplendent Spark, which you can then use to craft more gear.
With two Resplendent Sparks (and about 50M Gold), you can craft a random Mythic Unique from the Blacksmith. If you want to get something specific, visit the Jeweller and use two Resplendent Sparks and some specific runes to get the item you want.
Mythic Prankster
There’s a very rare chance that you’ll find a Mythic Prankster Treasure Goblin while running Nightmare Dungeons. Killing these guys will make them drop five Mythic Uniques plus a bag containing more. Mythic Pranksters are extremely rare, but in our case, we found one just 19 Paragon Levels into our first character in Season 11. These goblins can appear in any Nightmare Dungeon, regardless of what key you have or where you get them from.
